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Updated: Jul 12, 2026

Live Imaging of Drug Responses in the Tumor Microenvironment in Mouse Models of Breast Cancer
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多参数成像揭示了临床相关的癌细胞与瘤相互作用动态

Karolina Punovuori1, Fabien Bertillot2, Yekaterina A Miroshnikova3

  • 1Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.

Cell
|October 29, 2024
PubMed
概括

这项研究揭示了癌细胞及其周围的肌层如何相互作用,驱动头支状细胞癌 (HNSCC) 的侵袭. 了解这些相互作用为预测和治疗HNSCC提供了新的途径. 关键词:癌细胞,肌瘤,HNSCC,攻击性,治疗.

关键词:
癌症癌症生物标志物癌症干细胞从上皮细胞转变为介质细胞

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相关概念视频

The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...