RIPK1 TNF

Na Zhang1, Jianping Liu2, Rui Guo2

  • 1Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China; University of Chinese Academy of Sciences, Beijing 101408, China.

Molecular cell
|October 29, 2024
PubMed
概括

S-palmitoylation激活了与受体相互作用的氨酸/氨酸蛋白激酶1 (RIPK1) 激酶活性,在细胞死亡检查点失败时驱动炎症性疾病. 这种由DHHC5介导的修改为这些疾病提供了潜在的治疗点.

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