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Updated: Jun 9, 2025

A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4
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对于β-阿雷斯的受体决定者 功能特异性在C-X-C 化学受体5

Joseph M Crecelius1, Aaren R Manz1, Sara Benzow1

  • 1Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin.

Molecular pharmacology
|October 29, 2024
PubMed
概括

β-阿雷斯被招募到C-X-C基因化学因子受体5 (CXCR5) 中,对其无敏化至关重要. 然而,这些蛋白质对于CXCR5的内部化或信号传递是不必要的,突出显示了不同功能的不同受体决定因素.

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