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Updated: Jun 21, 2026

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy
09:40

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy

Published on: October 4, 2019

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一种使用单细胞RNA测序的质母细胞瘤多形吸引体潜在的in silico探索方法

Marcos Guilherme Vieira Junior1, Adriano Maurício de Almeida Côrtes2,3, Flávia Raquel Gonçalves Carneiro4,5,6

  • 1Graduate Program in Computational and Systems Biology, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, 21040-900, Brazil. marcosvieira.research@gmail.com.

Scientific reports
|October 30, 2024
PubMed
概括

这项研究引入了一种新的方法,使用单细胞RNA测序 (scRNA-seq) 数据来识别癌症吸引因子,从而提供了对多种质母细胞瘤 (GBM) 异质性和潜在治疗点的见解.

关键词:
生物标志物 生物标志物吸引癌症的因素 吸引癌症的因素值得信赖的地区质母细胞瘤多形多稳定性 多稳定性单细胞RNA测序的一个细胞.

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Nuclei Isolation from Fresh Frozen Brain Tumors for Single-Nucleus RNA-seq and ATAC-seq06:22

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相关概念视频

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...