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使用聚硫硫酸催化剂合成 furan-2-ones 和 spiro[furan-2,3'-indoline] 衍生物

Seyed-Mola Khatami¹, Mehdi Khalaj², Maryam Zarandi³

¹Department of Chemical Industry, Technical and Vocational University (TVU), Tehran, Iran.

Scientific reports

|October 30, 2024

概括

一种新型的聚硫硫酸 (PES-NHSO3H) 催化剂可以有效合成 furan-2-ones 和 spiro[furan-indoline]衍生物. 这种可重复使用的催化剂在多个反应周期中表现出高产量和稳定性.

科学领域:

有机化学有机化学
材料科学材料科学材料科学
催化剂是一种催化剂.

背景情况:

开发高效且可重复使用的酸催化剂对于可持续的有机合成至关重要.
聚硫 (PES) 基材料为各种应用提供可调节的性能.
硫化引入了强烈的酸性位点,增强了催化活性.

研究的目的:

合成和描述聚硫硫酸 (PES-NHSO3H) 作为一种新型固体酸催化剂.
评估 PES-NHSO3H 在功能化 furan-2-one 和 spiro[furan-indoline] 衍生物的合成中的催化性能.
研究PES-NHSO3H催化剂的可重复使用性和稳定性.

主要方法:

改性聚乙烯硫的简单硫化,以制备PES-NHSO3H.
酸定位和硫酸试验以量化酸性位点 (SO3H).
三组分反应涉及阿尼林,化物/1-乙烯二,3-二和二乙烯乙烯二碳酸盐.

主要成果:

PES-NHSO3H成功合成了高密度的酸性位点 (4.234.29 mmol H+/g).
催化剂促进了高产率 (8597%) 的目标化合物的合成.
催化剂表现出很好的可重复使用性,在11个回收周期后,没有失去催化潜力.

结论:

PES-NHSO3H作为一种高效,可回收和稳定的固体酸催化剂,用于合成有价值的有机化合物.
这项研究强调了硫化聚硫材料在绿色化学应用中的潜力.
成功研究了溶剂对反应生产率的影响,优化了反应条件.

关键词:

2′,5-Dioxo-5H-spiro[furan-2,3′-indoline]-3-carboxylate衍生物的2′,5-Dioxo-5H-spiro[furan-2,3′-indoline]-3-carboxylate衍生物的2′,5-Dioxo-5H-spiro[furan-2,3′-indoline]-3-carboxylate衍生物的2′,5-Dioxo-5H-spiro[furan-2,3′-indoline]-3-carboxylate衍生物的2′,5-Dioxo-5H-spiro[furan-2,3′-indoline]-3-carboxylate衍生物的2′,5-Dioxo-5H-spiro[furan-2,3′-indoline]-3-carboxylate衍生物的2′,5-Dioxo-5H-spiro[furan-2,3′-indoline]-3-carboxylate衍生物的2′,5-Dioxo-5H-spiro 基化物 (Butenolides) 是一种基化物 furan-2-ones 是一种-2-ones 的类型.聚乙硫硫酸硫胺酸的使用情况螺旋化合物是螺旋化合物中的一种.

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