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相关概念视频

Somatic Spinal Reflexes01:22

Somatic Spinal Reflexes

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Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
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Thoracic Spinal Cord Hemisection Surgery and Open-Field Locomotor Assessment in the Rat
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在脊髓截断后,运动和感觉运动反射的发育变化.

Alleyna C Martes1, Aimee L Bozeman1, Julie Doell1

  • 1Department of Psychology, Idaho State University, Pocatello, Idaho, USA.

Developmental psychobiology
|October 30, 2024
PubMed
概括

新生小鼠的脊髓切割揭示了腰椎脊髓.

关键词:
行为行为行为行为.新生儿新生儿新生儿新生儿这是一个开放的田野.收回回收回收的恢复传感器运动器传感器脊髓损伤导致的脊髓损伤

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Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats
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Author Spotlight: Using the MouseWalker to Quantify Locomotor Dysfunction in a Mouse Model of Spinal Cord Injury
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科学领域:

  • 神经科学是一个神经科学.
  • 发展生物学 发展生物学
  • 再生医学是一种再生医学.

背景情况:

  • 脊髓损伤 (SCI) 影响感觉运动功能的发展.
  • 第二个产后周对于大鼠的脊柱感觉运动发育和恢复至关重要.
  • 新生儿SCI后的可塑性机制尚不清楚.

研究的目的:

  • 在SCI后,在产后第二周内,对承重运动和感觉运动反射的发育变化进行表征.
  • 为新生儿SCI建立未来研究和潜在干预措施的基线.

主要方法:

  • 完整的低胸部脊髓切割 (T8-T10) 或在出生后的一天在老鼠的假手术1.
  • 在出生后的7,14,21天评估自发运动,后肢承重,和感觉运动反射 (表面直,后肢放置,交叉伸展反射).

主要成果:

  • 脊椎切割和假老鼠表现出类似的自发运动,但随着时间的推移,后肢承重模式不同.
  • 患有SCI的新生小鼠表现出保存的感觉运动反射,表明隔离的腰椎脊髓的功能能力.

结论:

  • 新生儿的腰椎脊髓仍然有能力处理感官输入,并在切割后产生协调的运动输出.
  • 了解这些发育轨迹对于开发有效的干预措施来改善儿科SCI后的功能恢复至关重要.