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Updated: Jun 9, 2025

Biochemical Purification and Proteomic Characterization of Amyloid Fibril Cores from the Brain
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Biochemical Purification and Proteomic Characterization of Amyloid Fibril Cores from the Brain

Published on: April 28, 2022

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揭示了氨基胺核心接口的复杂性

Máté Sulyok-Eiler1,2, Veronika Harmat1,3, András Perczel4,1,3

  • 1Laboratory of Structural Chemistry and Biology, Institute of Chemistry, ELTE Eötvös Loránd University, Pázmány P. stny. 1/A, H-1117 Budapest, Hungary.

Journal of chemical information and modeling
|October 30, 2024
PubMed
概括

本研究介绍了一个数据库和分析工具,用于形成粉样结构的聚合易感区域 (APR). 结果揭示了平行与反平行β-sheet接口的独特特征,有助于粉样蛋白设计.

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