运行一个不良事件检测监测系统,以支持抗微生物药物管理活动:从SHEA研究网络的感知和见解
Hawra J Al Lawati1, Kimberly L Harvey2, Marlena Shin2
1Beth Israel Deaconess Medical Center, Boston, MA, USA.
Infection control and hospital epidemiology
|October 30, 2024
概括
开发一个患者级别的抗微生物药物不良药物事件 (ADE) 监测系统对于抗微生物药物管理至关重要. 专家们更喜欢简单的,基于实验室的ADE定义,尽管存在可行性和归因方面的挑战.
科学领域:
- 药物监督 药物监督 药物监督
- 医疗信息学 医疗信息学
- 抗微生物药物管理委员会
背景情况:
- 患者级抗微生物药物不良药物事件 (ADEs) 监测可以加强抗微生物药物管理.
- 关于ADE监控系统的设计和实施的关键问题仍然存在.
研究的目的:
- 对抗微生物药物管理专家进行调查,了解他们对设计ADE监控系统的偏好.
- 为了确定专家意见在ADE定义简单性,可行性和临床重要性之间的最佳平衡.
主要方法:
- 在抗微生物药物管理专家中进行了一项全国性调查.
- 调查的重点是对ADE定义的偏好,考虑了实验室标准,图表审查的必要性和归因挑战等因素.
主要成果:
- 监管专家普遍赞成更简单的,基于实验室的ADE监控定义.
- 关于这些定义的可行性,在不进行广泛的图表审查的情况下确定归因的能力,以及特定ADEs的临床意义的紧张关系被确定.
结论:
- 虽然专家倾向于更简单的,基于实验室的ADE监控定义,但实际实施的挑战需要进一步考虑.
- 为了有效的管理支持,需要平衡可行,可归因的ADE检测与特定事件的临床重要性.
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