在卵泡相对黄体阶段腹腔镜内膜瘤切除后比较卵巢储备参数:一个前性队列研究
Ozguc Takmaz1, Mehmet Resit Asoglu2, Mehmet Ceyhan1
1Department of Obstetrics and Gynecology, Maslak Hospital, Acibadem Mehmet Ali Aydinlar University, School of Medicine, İstanbul, Türkiye.
Frontiers in medicine
|October 30, 2024
概括
腹腔镜内膜瘤手术的时间不会影响卵巢储备. 毛囊和质期手术在手术后六个月对抗穆勒尔激素 (AMH) 水平和毛囊数量 (AFC) 产生了类似的影响.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 最少侵入性的手术
- 妇科瘤学 妇科瘤学
背景情况:
- 子宫内膜瘤是常见的妇科疾病.
- 腹腔镜手术是对子宫内膜瘤的标准治疗方法.
- 与月经周期相对而言,手术的最佳时间还没有得到很好的定义.
研究的目的:
- 为了调查月经周期的阶段 (卵泡与白细胞),在此期间进行腹腔镜内膜瘤手术是否会影响卵巢储备的变化.
- 为了比较在不同阶段手术的患者之间手术后的抗穆勒尔激素 (AMH) 水平和毛囊数 (AFC).
主要方法:
- 一项前性队列研究包括55名接受单边腹腔镜内膜瘤切除的妇女.
- 参与者被分为卵泡阶段组 (n=28) 和白色细胞阶段组 (n=27).
- 卵巢储备标志物 (AMH和AFC) 在手术前和手术后6个月被评估.
主要成果:
- 在两组中,AMH和AFC在手术后6个月显著下降 (p <0.05).
- 在毛囊 (24.5%) 和黄体 (19.5%) 组之间,AMH水平下降的速度没有显著差异 (p > 0.05).
- 同样,在毛囊 (13.4%) 和黄体 (14.3%) 组 (p > 0.05) 中,AFC 减少的速度是可比的.
结论:
- 腹腔镜内膜瘤手术的时间,无论是在卵泡或状细胞阶段,似乎不会显著影响卵巢储备的变化.
- 这些发现表明,手术安排可以基于临床方便而不是月经周期阶段来保持卵巢功能.
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