C-反应蛋白/白蛋白比率预测了短期的术后结果和结肠直肠穿孔中的腹腔形成
Takuya Shiraishi1, Takahiro Seki1, Chika Katayama1
1Department of General Surgical Science, Gunma University Graduate School of Medicine, Maebashi, Japan.
Journal of the anus, rectum and colon
|October 30, 2024
概括
反应蛋白 (CRP) /白蛋白比率 (CAR) 可以预测结直肠穿孔患者的术后并发症和死亡率. 一个CAR值为4.9或更高表明风险增加,指导改善的外科手术结果.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 关键护理医学 关键护理医学
背景情况:
- 结直肠穿孔是一种严重的疾病,需要紧急手术.
- 预测术后结果对于患者的管理和预后至关重要.
研究的目的:
- 调查手术前的因素,特别是C-反应蛋白 (CRP) /白蛋白比率 (CAR),与接受结直肠穿孔紧急手术的患者的术后结果相关.
- 确定改善术后预后的潜在预测因子.
主要方法:
- 对28名连续接受了结直肠穿孔紧急手术的患者进行了回顾性分析.
- 调查与术后结果相关的临床因素,包括CAR.
- 多变量分析以确定并发症的独立风险因素.
主要成果:
- 鉴定出C反应蛋白 (CRP) /白蛋白比率 (CAR) 是术后并发症的一个独立风险因素 (OR,1.357;p=0.017).
- 4.9的CAR截止值预测了手术后并发症 (所有类型和Clavien-Dindo等级II或更高) 和住院死亡率的更高发生率.
- 术后第3天CAR升高与腹内的发病率较高有关.
结论:
- 术后CAR是患有结直肠穿孔的患者术后并发症和死亡率的有价值的预测指标.
- 使用CAR可能有助于改善这些患者的术后预后.
- CAR可以作为风险分层和管理调整的潜在生物标志物.
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