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肩部微生物组:一个系统的审查和元分析
Rajpal S Narulla1, Xiaolong Chen1,2,3, Ashish D Diwan1,2
1St George and Sutherland Clinical School, The University of New South Wales, Sydney, NSW, Australia.
JSES reviews, reports, and techniques
|October 30, 2024
概括
本地肩关节的微生物群,超过50%的样本显示有机体,如C. acnes. 这一发现影响了对肩部状况和手术结果的理解.
科学领域:
- 整形外科的研究研究.
- 微生物组研究 微生物组研究
- 人体生理学 人体生理学
背景情况:
- 肩膀关节曾经被认为是无菌的,现在已知它拥有本地微生物组.
- 常见的肩部疾病,如骨关节炎和旋转手套撕裂的病因仍然不清楚.
- 肩部微生物组可能在关节健康或疾病发病过程中发挥作用.
研究的目的:
- 系统地审查和描述有关原生肩关节微生物组的现有研究.
- 巩固关于微生物存在,常见生物和殖民率的发现.
- 评估肩部微生物组与术后结果之间的关系.
主要方法:
- 对Medline,Embase,Cochrane和SCOPUS数据库进行系统审查和元分析.
- 使用"肩膀"",微生物群"",感染"和"殖民化"等术语进行搜索.
- 包括接受手术的非手术肩膀的人类研究;不包括评论,动物和尸体研究.
主要成果:
- 分析了47项涉及3283名患者的研究.
- 原生肩部样本在50.8%的病例中显示有机体,主要是C. acnes.
- 皮肤制备使殖民率从55.7%降至43.5%,术后感染率为1.8%.
结论:
- 强有力的证据支持本地肩部微生物组的存在.
- 需要进一步的研究来充分描述这种微生物组.
- 了解肩部微生物组可以为肩部病理的治疗提供信息.
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