湿疹性食道炎的组织学表现:仅仅是一个神奇的数字?
William Sterlacci1, Michael Vieth1, Markus Neurath2
1Institute of Pathology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Klinikum Bayreuth, Bayreuth, Germany.
Inflammatory intestinal diseases
|October 30, 2024
概括
生性食道炎 (EoE) 是一种成长的疾病. 本文讨论了诊断EoE的组织学标准,这对于临床研究和日常护理至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
背景情况:
- 在工业化国家,性食道炎 (EoE) 越来越普遍.
- 虽然以前被认为是酸性胃肠炎的一部分,但EoE现在被认为是一个独特的实体,通常只影响食道.
- 有效的免疫抑制和免疫调节疗法可以诱导EOE患者的症状缓解和缓解.
研究的目的:
- 评估目前用于诊断eosinophilic食道炎的组织学标准的实用性和可行性.
- 讨论在临床研究和标准医疗实践中对酸性食道炎分级的要求.
主要方法:
- 审查和讨论现有的组织学诊断标准,以性食道炎.
- 对临床研究和常规诊断设置的分级要求的分析.
主要成果:
- 这篇文章批判性地检查了用于诊断eosinophilic食道炎的组织学标准的价值和实用性.
- 它解决了在临床试验和日常患者护理中对这种疾病进行分级的具体需求.
结论:
- 标准化和实用的组织学标准对于准确的eosinophilic食道炎诊断和管理至关重要.
- 为了在研究和临床实践中进行一致的评估,需要明确的分级要求.
相关概念视频
Barrett Esophagus-I: Introduction
70
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
70
Barrett Esophagus-II: Clinical Manifestations and Management
112
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
112
Histology of the Small Intestine
546
The small intestine exhibits a unique histological structure that significantly enhances its function in digestion and nutrient absorption. These structures include circular folds, villi, and various specialized cells that collectively facilitate the digestion of food.
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
546
Esophageal Strictures-I: Introduction
66
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
66
Histology of the Gastrointestinal (GI) Tract
734
The GI tract, from beginning to end, is made up of four continuous tissue layers that adjust their structure according to their specific roles. These layers, from innermost to outermost, are known as the mucosa, submucosa, muscularis, and serosa, which are continuous with the mesentery.
The mucosa is sometimes called a mucous membrane due to its mucus-secreting features. This membrane is composed of epithelium, which directly interacts with ingested substances, and the lamina propria, a layer...
The mucosa is sometimes called a mucous membrane due to its mucus-secreting features. This membrane is composed of epithelium, which directly interacts with ingested substances, and the lamina propria, a layer...
734
Esophageal Strictures-II: Clinical Features and Management
51
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
51


