评估胃肠道病理的年龄相关风险:几十年来胃镜检查结果的比较研究
Lac Nguyen1, Noora Räsänen1, Filippa Berggren1
1Division of Gastroenterology, Department of Internal Medicine, and University Health Care Research Unit, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
消化管胃管腺镜检查 (EGD) 对于诊断上部肠道问题至关重要. 这项研究发现,虽然老年患者 (61-70) 有更多的病理,但癌症风险并没有显著增加,这表明更广泛地使用"测试和治疗"策略.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 消化管胃管腺镜 (EGD) 是诊断上部胃肠道 (GI) 病理的黄金标准.
- 瑞典的指导方针建议EGD用于50岁以上的新发性消化不良症状的个人,以排除恶性瘤.
- 在61至70岁的年龄组中,发育不良或癌症的发生率需要进一步调查.
研究的目的:
- 检查61-70岁患者的转诊因子和内镜检测结果.
- 将这些发现与年轻年龄组 (51-60和41-50) 的结果进行比较.
- 为了确定是否有一个年龄切断存在于上部胃肠道癌症风险增加.
主要方法:
- 一项回顾性观察性研究分析了2019年1月至2020年4月和2022年1月至2023年1月的1003个EGD转诊情况.
- 收集和统计分析了临床数据,症状,药物和实验室结果.
- 几率比率 (OR) 和正预测值 (PPV) 用于根据转诊因子来评估病理结果.
主要成果:
- 在41-50参考组和老年组 (51-60: OR 2.08; 61-70: OR 3.05) 之间,在病理发现中发现了统计学上显著的差异.
- 在各年龄组之间没有观察到癌症发病率的统计学上显著差异.
- 良性发现,如椎,GERD/食道炎和胃炎是最常见的.
结论:
- 在所有研究的年龄组中,癌症的发病率仍然很低.
- 老年患者病理发现的可能性增加主要是由于良性疾病.
- 目前的"测试和治疗"策略,用于50岁以下的患者,可能适用于51-70岁的个人.
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相关概念视频
Assessment of the Gastrointestinal System I: Subjective Data
Health History
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Assessment of the Gastrointestinal System II: Health Perception Pattern
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Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
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Endoscopic Procedures I: Esophagogastroduodenoscopy
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