在患有左半球慢性囊性和突性中风患者的thalamic功能失联
Jun Guo1,2, Hongchuan Zhang2,3, Jingchun Liu2
1Department of Radiology, Tianjin Huanhu Hospital and Tianjin University HuanHu Hospital, Tianjin, China.
Frontiers in neuroscience
|October 30, 2024
概括
脑中风后的脑功能连接性变化取决于病变位置和特定的脑子部分. 囊性和突性脑筋中风都显示出缩性和缩性 thalamus 的连接性发生变化.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 放射学 放射学是一门学科.
背景情况:
- 泰拉马斯是皮层-皮下电路的关键枢纽,参与各种大脑功能.
- 囊中风和突中风对乳头功能连接的具体影响尚不清楚.
研究的目的:
- 研究囊中风 (CS) 和关中风 (PS) 对体功能连接 (FC) 的差异性影响.
- 探讨慢性中风患者的改变的体FC和临床结果之间的关系.
主要方法:
- 招募了66名慢性中风患者 (46名CS,20名PS) 和67名健康对照.
- 使用双向重复ANOVA分析了thalamic子场FC,控制了混因子.
- 使用斯皮尔曼部分相关性,与临床变量相关联改变的FC.
主要成果:
- 脑脊髓病患者表现出认知区域的 FC 降低,感官运动区域的 FC 增加.
- PS患者主要在感觉运动区域表现出增加的FC.
- 两个CS和PS组都显示了相似的,虽然不那么广泛的,FC变化在收缩性 thalamus. 观察到显著的x组子场相互作用,表明不同的失联模式.
结论:
- 慢性中风中的thalamic功能失联性取决于病变位置和特定的thalamic子领域.
- 改变的FC模式在ipsilesional和contralesional thalami中都被观察到,具有相似的特征.
- 在thalamic FC和运动,工作记忆和口头记忆功能之间发现了弱相关性.
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