门内镜性肌肉切除作为基利安-贾米森分离器 (KJ-POEM) 的治疗方法
Redeat Libanos Assefa1, Michael Bejjani2, Amit Mehta3
1Gastroenterology, Johns Hopkins University, Baltimore, United States.
Endoscopy international open
|October 30, 2024
概括
基利安-贾米森口腔内镜肌切除术 (KJ-POEM) 为基利安-贾米森分离器 (KJD) 提供了一种安全有效的治疗方法. 这种微创手术在解决症状方面取得了很好的短期到中期成功,没有不良事件.
科学领域:
- 胃肠病学 胃肠病学
- 最少侵入性的手术
- 食道疾病 食道疾病
背景情况:
- 基利安-贾米森分泌管 (KJD) 是一种罕见的食道疾病.
- 手术肌肉切除一直是症状性KJD的传统治疗方法.
- 最少侵入性的内镜技术,如KJ-POEM,是新兴的替代方案.
研究的目的:
- 为了评估KJ-POEM对症状性KJD的有效性.
- 评估KJ-POEM在KJD治疗中的安全性.
- 确定KJ-POEM的短期和中期成果.
主要方法:
- 国际,多中心,回顾性研究.
- 包括接受KJ-POEM治疗症状KJD的患者 (2018年10月至2023年4月).
- 主要结局:临床成功 (Kothari-Haber评分≤2);次要结局:技术成功,不良事件,症状复发.
主要成果:
- 13名患有KJD的患者接受了KJ-POEM.
- 实现了100%的临床和技术成功.
- 平均术后Kothari-Haber评分为0.91;没有不良事件或重复的喉神经损伤.
- 平均住院时间为1.09天;在平均9.41个月的随访期内,没有症状复发.
结论:
- KJ-POEM是一种安全有效的治疗症状的KJD.
- 该程序显示了优秀的短期到中期结果.
- KJ-POEM代表了传统手术的可行替代方案.
关键词:
内镜 上部消化道 上部消化道
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