慢性乙型肝炎:在没有回归点之前预防,诊断和治疗
Sudheer Marrapu1, Ramesh Kumar2
1Department of Gastroenterology, All India Institute of Medical Sciences, Patna 801507, India.
World journal of hepatology
|October 30, 2024
概括
慢性乙型肝炎 (CHB) 影响全球2.54亿人,低诊断和治疗率阻碍了世卫组织的行动.
科学领域:
- 肝病学和传染病的研究
- 全球公共卫生 全球公共卫生
背景情况:
- 慢性乙型肝炎 (CHB) 影响全球大约2.54亿人,导致显著的发病率和死亡率.
- 乙型肝炎病毒 (HBV) 感染的认识和诊断率仍然非常低,特别是在撒哈拉以南非洲 (1%的认识).
- 在2022年,CHB导致全球110万人死亡,这凸显了其持续的公共卫生威胁.
研究的目的:
- 突出阻碍世界卫生组织 (WHO) 消除乙型肝炎作为公共卫生问题的2030年目标的重大挑战.
- 为强调改善乙型肝炎诊断,治疗准入和疫苗接种覆盖率的迫切需要.
- 强调及时的HBV干预的重要性,以最大限度地提高治疗效益,并预防晚期肝病.
主要方法:
- 这篇社论综合了关于CHB的全球负担的当前数据.
- 它审查了B型肝炎护理的现有挑战,包括疫苗接种,诊断,治疗资格,医疗保健准入和成本.
- 它分析了疾病阶段对治疗疗效的影响.
主要成果:
- 世卫组织2030年消除肝炎的目标面临重大障碍.
- 在全球范围内,只有不到13.4%的CHB患者被诊断为CHB.
- 当CHB进展为肝硬化时,治疗效益大大减少.
结论:
- 实现到2030年消除乙型肝炎需要解决疫苗接种,诊断和治疗的关键差距.
- 早期检测和干预对于有效的HBV管理和改善患者结果至关重要.
- 迫切需要多方面的战略来克服目前在乙型肝炎护理方面的障碍.
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