青春期暴露于工业空气污染与年轻成年人癌症的关联
Ruth Lev Bar-Or1, Yuval2,3, Gilad Twig4,5,6,7
1Braun School of Public Health and Community Medicine, The Hebrew University of Jerusalem-Hadassah, Jerusalem 9112102, Israel.
Environment & health (Washington, D.C.)
|October 30, 2024
概括
靠近海法湾地区的工业空气污染与青春期暴露的成年人癌症风险增加有关. 这项研究强调了石化行业排放对长期健康的潜在致癌影响.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 毒理学 毒理学 毒理学
背景情况:
- 公众对石油化学工业附近的健康风险存在担忧.
- 海法湾区 (HBA) 拥有以色列最密集的工业区和高癌症死亡率.
- 自20世纪60年代末以来,癌症死亡率的增加加剧了以前的担忧.
研究的目的:
- 调查青少年暴露于HBA中的工业空气污染和成人发病癌症之间的联系.
- 评估石化行业排放对健康的长期影响.
主要方法:
- 使用以色列医疗队伍数据和以色列国家癌症登记册对2,187,317名受试者的历史队列研究.
- 随访期延长至45年.
- 暴露评估使用了二氧化硫 (SO2) 作为空气污染分散的标记物的空间战争插值模型.
主要成果:
- 增加原始 (HR=1.23) 和调整 (HR=1.16) 的癌症风险,与HBA中的更高空气污染暴露相关.
- 协会在不同的十年和社会经济地位中保持了强的地位.
- 单调地增加了白血病,黑色素瘤,女性乳腺,中枢神经系统和甲状腺癌的风险.
结论:
- 在青春期暴露于HBA中的工业空气污染,存在致癌风险.
- 这些发现支持了将石化排放与癌症发病率增加联系在一起的假设.
- 在工业区,环境监测和公共卫生干预是有必要的.
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