局部类固醇用于抑制烧伤中的超粒度:大西洋两岸的趋势
Yoram Shoham1, Paul Comish2, Rotem Tsur1
1Department of Plastic and Reconstructive Surgery, Soroka University Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel.
概括
局部皮质类固醇在欧洲比北美更频繁地用于燃烧高颗粒化. 这种差异源于欧洲的临床医生认为类固醇更安全,更有效,尽管在两个地区报告的类似的低副作用.
科学领域:
- 烧伤护理 烧伤护理
- 伤口愈合 治愈 伤口愈合
- 皮肤病学 皮肤病学
背景情况:
- 过度颗粒化的伤口是烧伤患者的重要并发症.
- 目前用于燃烧后超颗粒化的治疗方法缺乏标准化.
- 局部皮质类固醇的使用在地理上是可变的和争论的.
研究的目的:
- 在北美和欧洲量化局部皮质类固醇用于烧伤后高颗粒的使用.
- 评估临床医生对局部皮质类固醇在烧伤护理中的安全性和有效性的看法.
- 找出治疗方法的区域差异的潜在原因.
主要方法:
- 一项调查分发给欧洲和美国烧伤协会的成员.
- 分析了来自165名受访者 (90名欧洲,75名北美) 的数据.
- 使用SPSS软件进行了统计分析.
主要成果:
- 欧洲受访者 (78.9%) 经常使用局部类固醇,而北美受访者 (33.3%) (p<0.001).
- 欧洲的临床医生更有可能将局部类固醇视为安全 (100%vs74.4%) 和有效 (98.6%vs66.7%) (p<0.001).
- 报告的系统性影响在区域之间没有显著差异 (6.5%与6.9%,p>0.10).
结论:
- 局部皮质类固醇用于烧伤高颗粒化在欧洲比北美更为普遍.
- 感知到的安全性和有效性的差异可能解释了不同的使用率.
- 尽管实践不同,但局部类固醇使用相关的不良影响似乎很小,并且在不同地区是可比的.
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