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Updated: Jun 9, 2025

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair

Published on: October 6, 2014

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在BRCA1和BRCA2病原性变异载体中,乳腺癌之后的第二种主要癌症风险

Isaac Allen1,2, Hend Hassan1,2, Yvonne Walburga1,2

  • 1Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, United Kingdom.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
|October 30, 2024
PubMed
概括

患有BRCA1/BRCA2致病变体 (PVs) 的女性在乳腺癌 (BC) 中存活下来,面临着第二次原发性癌症 (SPCs) 的风险增加. 对于这些高风险个体,建议加强监测和降低风险的策略.

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Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA108:53

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1

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