复杂的皮肤和皮肤结构感染在酒者,一个回顾性队列研究
Klaus Kessel1, Iiro Jääskeläinen1, Lars Hagberg2,3
1Division of Infectious Diseases, Inflammation Center, Helsinki University Hospital, Helsinki, Finland.
Infectious diseases (London, England)
|October 30, 2024
概括
酒与更严重的复杂皮肤和皮肤结构感染 (cSSSIs) 有关,导致医疗保健使用率增加. 尽管并发症的发病率较高,但酒精和非酒精患者的死亡率相似.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 临床医学 临床医学
背景情况:
- 酒是皮肤和皮肤结构感染 (SSSIs) 的已知危险因素.
- 酒与复杂SSSIs (cSSSIs) 的较差结果有关,包括延迟治疗和增加血液培养阳性.
- 酒精消费对肺炎和细菌病的结果产生负面影响,与较高的死亡率和长时间住院相关.
研究的目的:
- 为了比较患者和疾病因素,治疗和酒精与非酒精患者的治疗结果.
- 调查酒对cSSSIs严重程度和资源利用的影响.
主要方法:
- 基于人口的回顾性队列研究.
- 包括460例cSSSIs在瑞典哥德堡和芬兰赫尔辛基 (2008-2011) 接受治疗的病例.
- 将患者分为酒精 (9%) 和非酒精 (91%) 组进行比较分析.
主要成果:
- 酒精患者更年轻,更常见的是男性,肝脏疾病的发病率更高.
- 在酒精中观察到更高的细菌病发病率,重症监护室入院,手术干预和临床失败.
- 酒与更长的住院时间和增加的部门间转移有关,但与感染类型或诊断时间无关.
结论:
- 酒与cSSSIs中疾病严重程度的增加有关.
- 酒导致对cSSSI的医疗保健资源利用率更高.
- 虽然酒会增加cSSSI的严重程度和资源使用,但死亡率在各组之间是可比的.
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