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Updated: Jun 9, 2025

Cell Death Associated with Abnormal Mitosis Observed by Confocal Imaging in Live Cancer Cells
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卡斯巴-2 杀死具有额外中心体的细胞

Dario Rizzotto1, Vincenza Vigorito2, Patricia Rieder1

  • 1CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria.

Science advances
|October 30, 2024
PubMed
概括

额外的中心体在细胞动力失败的血液细胞中触发了卡斯帕-2-驱动的亡,防止了致病性多倍化. 这种细胞死亡途径涉及PIDDosome复合体和BID处理,突出显示中心体.

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