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Updated: Jun 9, 2025

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降低的miR-486-5p通过促进SMAD2表达,参与脂聚糖诱导的HTR-8/SVneo细胞功能障碍

Yan Gu, Ling-Han Chen, Long Yang

    Reproduction (Cambridge, England)
    |October 30, 2024
    PubMed
    概括

    减少miR-486-5p的表达与早期妊娠丧失 (EPL) 相关,因为它会损害外性热囊细胞 (EVT) 侵袭并增加TNFα. 在LPS诱导的EVT功能障碍和EPL病变发生过程中,miR-486-5p/Smad2通路至关重要.

    关键词:
    这就是SMAD2的原因.早期怀孕期间的流产.奇异的热囊细胞.在 miR-486-5p 中使用.

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