作为由于相对能量缺乏而导致的脑下垂体功能障碍的第一个症状,治疗甲状腺功能低下的运动员的非典型甲状腺测试
Monika Skrzypiec-Spring1, Justyna Kuliczkowska-Płaksej2, Adam Szeląg1
1Department of Pharmacology, Wroclaw Medical University, Wrocław, Poland.
Endocrinology, diabetes & metabolism case reports
|October 30, 2024
概括
体育运动中的相对能量缺乏 (RED-S) 可以导致可逆性垂体功能障碍,影响运动员的甲状腺和生殖激素. 这种情况是由于能量摄入不足以满足高能耗需求造成的.
科学领域:
- 内分泌学 在内分泌学.
- 运动医学 运动医学
- 运动生理学 运动生理学
背景情况:
- 运动中的相对能量缺陷 (RED-S) 的特点是能量可用性不足.
- RED-S可以导致下丘脑-垂体-淋巴结核 (HPG) 轴的可逆抑制和下丘脑-垂体-甲状腺 (HPT) 轴的失调.
- 患有RED-S的运动员可能会表现出对生长激素的肝电阻,影响胰岛素样生长因子1水平.
研究的目的:
- 呈现一个临床案例的非典型的甲状腺功能测试在一个运动员与红色-S.
- 突出了运动员,特别是正常体重的运动员中RED-S的诊断挑战.
- 审查有关RED-S.临床过程和机制的文献.
主要方法:
- 一个33岁的运动员的临床案例介绍,他以前治疗过甲状腺功能低下症.
- 关于饮食和训练的采访.
- 实验室检测包括甲状腺功能和荷尔蒙评估.
- 关于 RED-S. 的文献综述
主要成果:
- 这名运动员出现了抑制的甲状腺刺激激素,低的自由三甲状腺素和正常的自由甲状腺素,这表明HPT轴失调.
- 确定了可逆性性阴性双胞胎症的证据,与能量可用性不足有关.
- 被诊断为RED-S,强调能量失衡对荷尔蒙功能的影响.
结论:
- 非典型的甲状腺功能测试可以是运动员RED-S和可逆性脑垂体功能障碍的早期迹象.
- 红色S影响运动员,无论体重如何,可以表现为荷尔蒙失调,包括HPT和HPG轴.
- 准确诊断RED-S需要仔细考虑与支出相关的能量可用性,即使在正常体重运动员中也是如此.
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