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Updated: Jun 9, 2025

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获得STAT1和STAT3功能:临床异质的免疫调节障碍

Peter Olbrich1,2, Alexandra F Freeman3

  • 1Sección de Infectología, Reumatología e Inmunología Pediátrica, UGC de Pediatría, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla/Universidad de Sevilla/Consejo Superior de Investigaciones Científicas, Red de Investigación Translacional en Infectología Pediátrica.

Current opinion in allergy and clinical immunology
|October 30, 2024
PubMed
概括

在STAT1和STAT3 (信号转换器和转录激活器) 中的功能获取突变影响宿主免疫力. 针对JAK/STAT通路的新疗法对自身免疫性疾病和感染有希望,尽管长期有效性需要进一步研究.

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