在非小细胞肺癌中分层分层术后风险的呼吸道萨尔科佩尼亚诊断
Changbo Sun1,2, Yoshifumi Hirata3, Takuya Kawahara4
1Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
呼吸道萨尔科佩尼亚是一种呼吸强度差且胸肌指数低的疾病,与非小细胞肺癌患者的病情恶化有关. 早期识别呼吸道可改善患者的管理和长期护理.
科学领域:
- 胸部外科手术 胸部外科手术
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
背景情况:
- 对于分层肺癌患者的物理生物标志物尚未得到充分研究.
- 呼吸道,以减少呼吸道肌肉强度和质量为特征,可能会影响手术结果.
研究的目的:
- 调查呼吸道的临床实用性,以优化非小细胞肺癌 (NSCLC) 患者的术后风险分层.
主要方法:
- 对806名经过带切除术的NSCLC患者进行了回顾性队列研究.
- 呼吸道萨尔科佩尼亚通过最大呼气流速和胸部肌肉指数 (PMI) 来评估.
- 短期和长期术后结果的比较,包括并发症和存活率.
主要成果:
- 在16.1%的患者中存在呼吸道.
- 增加了手术后并发症的风险 (30.0%) 和延迟的康复在呼吸道萨尔科佩尼亚的患者.
- 呼吸道肉症独立地与增加的死亡风险相关 (HR,1.83;95% CI,1.15-2.89).
结论:
- 呼吸道肉类是NSCLC患者在手术后出现不良结果的重要预测因素.
- 查呼吸道可识别高风险个体.
- 早期诊断和治疗呼吸道缩症可以优化治疗策略,改善NSCLC患者的纵向护理.
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