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Updated: Jun 9, 2025

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
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了解沃里康纳代谢:一个基于生理学和药物动力学建模的中期框架,整合了体外和临床见解

Ayatallah Saleh1,2,3, Josefine Schulz1, Jan-Frederik Schlender4

  • 1Department of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Berlin, Germany.

Clinical pharmacokinetics
|October 30, 2024
PubMed
概括

这项研究开发了一种基于生理学的药理动力学 (PBPK) 模型,以了解沃里可纳 (VRC) 代谢及其代谢物的影响. 该模型准确预测VRC度,改善治疗策略.

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