产前暴露于阿片类药物的新生儿管理:发展护理计划实施的影响
Gilles Cambonie1, Lison Aujogues Dit Baron2, Clementine Combes2
1Department of Neonatal Medicine and Pediatric Intensive Care, Arnaud de Villeneuve Hospital, Montpellier University Hospital, University of Montpellier, Montpellier, France; Pathogenesis and Control of Chronic Infection, INSERM UMR 1058, University of Montpellier, Montpellier, France.
Early human development
|October 30, 2024
概括
实施发育护理计划显著增加了产前阿片类药物暴露的婴儿的非药物治疗 (NPC). 这导致了减少药物使用和更短的住院时间,改善了新生儿阿片类药物戒断综合征 (NOWS) 管理.
科学领域:
- 新生儿医学 新生儿医学
- 发育儿科 发育儿科
- 药理学 药理学是指药理学的学科.
背景情况:
- 产前阿片类药物暴露的新生儿的传统管理依赖于药物治疗 (PT).
- 新兴的非药物治疗 (NPC) 方法缺乏广泛实施的证据.
- 这项研究旨在评估发育关怀计划对管理这些婴儿的影响.
研究的目的:
- 评估一项正式的发育护理计划对在子宫内暴露于阿片类药物的婴儿管理的影响.
- 评估使用非药物治疗 (NPC) 和药物治疗 (PT) 的变化.
- 确定对住院时间 (LOS) 和新生儿阿片类药物戒断综合征 (NOWS) 发生的影响.
主要方法:
- 在三级围产中心进行的观察性研究,比较了三个6年期 (2003-2020年).
- 收集的数据包括入住父母婴儿单位 (PIU),接触NPC和PT,NOWS,LOS和养类型.
- 干预影响通过比较计划实施和整合前,期间和之后的三个时期的结果来衡量.
主要成果:
- 从第一期到第三期,对NPC的暴露显著增加 (37%至84%,p < 0.001).
- 对PT (40%至15%,p=0.002) 和LOS (13至8天,p=0.003) 的暴露显著下降.
- 在PIU的住院和后来的研究期与没有PT有关.
结论:
- 支持NPC培训和实践的积极政策对于管理产前阿片类药物暴露的婴儿至关重要.
- 实施发育护理计划有效减少了药物使用和住院时间.
- NPC是改善新生儿在子宫内暴露于阿片类药物的结果的重要组成部分.
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