对焦虑症,强迫症和PTSD进行脑刺激的有效性和可接受性:随机对照试验的系统审查和网络元分析

对焦虑症,强迫症和PTSD进行脑刺激的有效性和可接受性:随机对照试验的系统审查和网络元分析

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Xinxin Yang¹, Lijun Ma², Chuan Fan³

¹Department of Psychiatry, Chaohu Hospital of Anhui Medical University, Hefei, Anhui, China; Department of Medical Psychology, School of Mental Health and Psychological Science, Anhui Medical University, Hefei, China.

Journal of affective disorders

|October 30, 2024

概括

大脑刺激技术 (BST) 对焦虑症,强迫症 (OCD) 和创伤后应激障碍 (PTSD) 显示出有效性. 低频重复性跨脑磁性刺激 (lf-rTMS) 似乎对这些情况最有希望.

科学领域:

神经科学是一个神经科学.
精神病学是一个精神病学.
医疗技术医疗技术医学技术

背景情况:

焦虑障碍,强迫症和PTSD显著影响心理健康.
对这些疾病的有效和可接受的治疗方法至关重要.
大脑刺激技术 (BST) 提供了潜在的治疗途径.

研究的目的:

系统地审查和网络分析BST对焦虑障碍,强迫症和PTSD的有效性和可接受性.
为了比较各种BST与假或健康对照.

主要方法:

在多个数据库 (Embase,PubMed,PsycINFO等) 中进行全面的文献搜索. 在2023年9月之前.
包括对深度大脑刺激 (DBS),电疗法 (ECT),重复性跨磁刺激 (rTMS) 和跨直流刺激 (tDCS) 的随机临床试验.
主要结局:有效性;次要结局:可接受性.

主要成果:

分析包括来自41个试验的1333名患者.
包括DBS,ECT,阴极tDCS,高频rTMS (hf-rTMS),阳极tDCS和低频rTMS (lf-rTMS) 在内的BST显示出比对照组更高的疗效.
在hf-rTMS,lf-rTMS和ECT中,接受度很高.

结论:

BST是治疗焦虑障碍,强迫症和PTSD的有效方法.
低频rTMS (lf-rTMS) 成为一个特别有前途的治疗选择.
未来的研究应该扩大BST和研究的参数的范围.

关键词:

焦虑症焦虑症焦虑症大脑刺激刺激大脑在 DBS 中,DBS 是 DBS 的代名词.美国欧洲欧洲欧洲欧洲在TMSMS中使用.tDCSCS 是一个很好的方法.

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