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使用心血管磁共振特征追踪的双纵向应变分析:艾森门格综合征的预后价值

Chao Gong¹, Chen Chen², Xuhan Liu²

¹Department of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, PR China; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, PR China.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

|October 30, 2024

概括

使用心血管磁共振 (CMR) 的双管管纵向应变分析可以预测艾森门格综合征 (ES) 的结果. 较低的应变值表明死亡率和心力衰竭的风险更高,改善了ES患者的风险分层.

科学领域:

心脏病学心脏病学
医疗成像医学成像
心血管疾病心血管疾病

背景情况:

由于证据有限,艾森门格综合征 (ES) 的风险分层仍然具有挑战性.
通过心血管磁共振 (CMR) 进行双管管纵向应变分析被提议作为ES的新型预后工具.

研究的目的:

调查艾森门格综合征患者中双心室纵向应变的预后价值.
评估双心脏功能受损与ES中不良临床结果之间的关联.

主要方法:

预计将招募57名ES患者,这些患者患有三柱后分流,正在接受CMR和右心导管治疗.
使用CMR特征追踪评估的双纵向菌株;复合终点包括死亡率和心力衰竭/血再入院.
考克斯回归,卡普兰-梅尔分析和C指数用于确定预后意义.

主要成果:

35.1%的患者在平均33个月的随访期间达到复合终点.
左下心室全球纵向应变 (LV GLS) 和右心室自由壁纵向应变 (RV FWLS) 与不良结果相关 (p < .05).
LV GLS和RV FWLS独立预测了复合终点,并与临床参数和喷射率 (C指数从0.75增加到0.86) 结合时改善了预后模型准确性.

结论:

损伤的双心室纵向菌株显著提高ES患者的预后预测,后三皮突变.
从CMR衍生出的双心室菌株分析为这种复杂人群的风险分层提供了宝贵的见解.

关键词:

心血管磁共振是一种心血管磁共振.艾森曼格综合征是艾森曼格综合征的一种疾病.功能跟踪功能跟踪功能跟踪预测预后预测预测压力应变是一种压力.

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