降低病原体血小板输血的安全性在临界病期和早产新生儿中
Alexia D'hont1,2, Ginette M Ecury-Goossen1, Ruben J Overduin3
1Department of Pediatrics, Subdivision of Neonatology, Curaçao Medical Center, Willemstad, Curaçao.
Vox sanguinis
|October 30, 2024
概括
米拉索尔减少病原体的血小板输血 (PRPTs) 对加勒比新生儿重症监护室 (NICU) 中的重症婴儿是安全的. 没有发现并发症或新感染,这表明PRPT是新生儿护理的安全选择.
科学领域:
- 新生儿重症监护室新生儿重症监护室
- 输血药物 输血药物 输血药物
- 预防传染病 预防传染病
背景情况:
- 血小板输血存在感染传播风险.
- 米拉索尔的病原体减少技术 (PRT) 使用利博弗拉和紫外线光消灭病原体和白细胞.
- 在脆弱的新生儿群体中评估PRPT的安全性至关重要.
研究的目的:
- 评估Mirasol减少病原体血小板输血 (PRPTs) 的安全性.
- 评估在新生儿重症监护室 (NICU) 设置中的重症病患婴儿的PRPT使用情况.
- 为了确定加勒比海NICU的安全概况.
主要方法:
- 进行了一项描述性回顾性研究.
- 从2016年2月到2023年4月收集的数据.
- 包括在库拉索的一家普通医院的NICU入院的患者.
主要成果:
- 208个PRPT给了46名患者 (中位数为3个输血/患者).
- 43名患者是早产 (中位妊娠年龄27 4/7周).
- 在24小时内,PRPTs耐受良好,没有血液溶解或新的感染; 46%的患者死亡,与PRPT无关.
结论:
- 米拉索尔PRPT在重症新生儿中证明了安全性.
- 该技术适用于极度早产的婴儿.
- 在新生儿重症监护中,PRPT提供了一种安全的输血选择.
相关概念视频
01:19Rh Blood Group
1.4K
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
1.4K
01:25Transmission-based Precautions II: Airborne and Protective Environment
1.2K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
1.2K
02:45Blood Transfusion and Agglutination
10.7K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
10.7K