日本市政工作人员的蔬菜和水果摄入量和LOX指数
Mirai Sakanari1, Masanori Ohta1,2, Mayumi Nagano2
1Graduate School of Health and Environmental Sciences, Fukuoka Women's University.
更高的蔬菜和水果摄入量可能会降低LOX指数,这是动脉样硬化进展的标志物. 这种关联在日本女性中显著,表明对心血管健康的性别特异性益处.
科学领域:
- 营养科学 营养科学
- 心血管疾病研究研究
- 生物标记分析 生物标记分析
背景情况:
- 蔬菜和水果消费与降低心血管疾病风险有关.
- 作为动脉样硬化进展的生物标志物和心血管事件的预测指标的LOX指数尚未与饮食有关的研究.
- 动脉样硬化是导致中风和冠心病的主要原因.
研究的目的:
- 调查蔬菜和水果摄入量与LOX指数之间的关联.
- 为了确定饮食习惯是否与动脉样硬化进展的关键生物标志物相关.
- 为了探索这种饮食关联中潜在的性别差异.
主要方法:
- 对338名日本市政公务员 (166名男性,172名女性) 的截面研究.
- 使用经过验证的简短自我管理的饮食史问卷来评估饮食摄入量.
- 洛克斯指数是从可溶性莱克类氧化LDL受体-1和LOX-1配合阿波利波蛋白B的配体的血清度计算出来的.
- 用于检查关联的多重回归分析,按性别分层.
主要成果:
- 在对共变量进行调整后,蔬菜和水果总摄入量呈现下降LOX指数的趋势 (趋势p=0.067).
- 在女性中发现了总蔬菜和水果摄入量与LOX指数之间的显著反向关联 (p为趋势=0.023).
- 在男性中没有观察到显著的关联 (p为趋势=0.70),也没有观察到特定的蔬菜或水果子组.
结论:
- 较高的蔬菜和水果总摄入量与日本女性较低的LOX指数有关.
- 富含蔬菜和水果的饮食模式可能在缓解动脉样硬化进展方面发挥作用,特别是在女性中.
- 需要进一步的研究来证实这些发现,并阐明潜在的机制.
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