银胺化物修饰的唾液对牙侵蚀的预防作用
Darren Dhananthat Chawhuaveang1, Walter Yu Hang Lam1, Chun Hung Chu1
1Cariology, Restorative Dental Sciences, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China.
概括
银二胺化物 (SDF) 与唾液皮质 (SP) 结合,显著减少牙侵蚀. 与单独的SDF或SP相比,这种SDF修饰的皮膜可以更好地保护牙和牙脱矿.
科学领域:
- 牙科生物材料科学 牙科生物材料科学
- 预防性牙科 预防性牙科
- 卡里斯研究研究研究.
背景情况:
- 牙侵蚀是一个重要的临床问题.
- 银胺化物 (SDF) 用于皮预防.
- 唾液 (SP) 在牙保护中起作用.
研究的目的:
- 评估银二胺化物 (SDF) 修改的唾液 (SP) 对牙侵蚀的预防作用.
- 研究SDF和SP对牙硬组织的协同作用.
- 评估SDF修改的SP对侵蚀性挑战的保护能力.
主要方法:
- 乳和牙块被分为四组:SDF+SP,SDF,脱离离子水 (DW) +SP和DW.
- 块经历了14天的侵蚀性挑战 (pH 3.2).
- 评估包括原子力显微镜 (AFM),X射线衍射 (XRD),微硬度测试,形状测量和扫描电子显微镜 (SEM).
主要成果:
- 经过SDF修改的SP显示皮质形态变化 (AFM).
- 检测到氧酸盐,银化物,银酸盐和银化物;酸盐是SDF+SP组 (XRD) 独有的.
- 与对照组相比,SDF+SP显著降低了微硬度损失的百分比 (%SMHL) 和牙和牙的表面损失 (p < 0.001的%SMHL,p = 0.031/0.002的表面损失).
- 在接受SDF治疗的组中,SEM显示了更光滑的牙面和部分牙管封闭.
结论:
- 银二胺化物 (SDF) 与唾液皮质 (SP) 具有积极的协同作用.
- 经过SDF修改的唾液皮膜可以增强对牙侵蚀的保护.
- 这种方法为防止牙侵蚀和非矿物化提供了一个有希望的策略.
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