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Updated: Jun 9, 2025

Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope
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Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope

Published on: March 24, 2017

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对单克隆抗体向CEACAM5表达瘤的表皮类-类相互作用的结构见解

Anand Kumar1, Francis Duffieux2, Marie Gagnaire2

  • 1Integrated Drug Discovery, Sanofi R&D, Paris, France.

Nature communications
|October 31, 2024
PubMed
概括

图萨米他马布拉坦辛通过结合其A3-B3域来准人类CEACAM5 (hCEACAM5). 结构分析揭示了关键的表皮质 - 侧皮质相互作用,使瘤中CEACAM5的特定向成为可能.

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