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Updated: Jun 9, 2025

A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations
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通过灵活的计算方法检测单细胞和空间转录学中的显著表达模式.

Hadas Biran1, Tamar Hashimshony2, Tamar Lahav2

  • 1Computer Science Department, Technion - Israel Institute of Technology, Haifa, Israel. hadas.moriah@gmail.com.

Scientific reports
|October 31, 2024
PubMed
概括

SPIRAL是一种新的算法,可以从单细胞,批量和空间转录组的基因表达数据中找到重要的生物过程. 它识别了基因细胞结构,揭示了其他方法错过的微妙但重要的生物学见解.

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Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
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