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Updated: Jun 9, 2025

Expression and Purification of the Human Lipid-sensitive Cation Channel TRPC3 for Structural Determination by Single-particle Cryo-electron Microscopy
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Published on: January 7, 2019

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异构体TRPC1/TRPC4通道的冷-EM结构

Jongdae Won1,2, Jinhyeong Kim3, Jinsung Kim3,4

  • 1Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul, Republic of Korea.

Nature structural & molecular biology
|October 31, 2024
PubMed
概括

研究人员揭示了人类TRPC1/TRPC4异构管道的冷EM结构. 这项工作阐明了TRPC通道异构化的分子结构,离子导电路和功能后果,包括减少的透性.

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