在儿童过敏喘中,ADAM33的基因特异性微RNA介导调节

Xiang Wen1,2, Juan Zhou1,2,3,4, Heping Fang1,2

  • 1Department of Respiratory Medicine, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.

Respirology (Carlton, Vic.)
|October 31, 2024
PubMed
概括

在ADAM33中,一种特定的遗传变异 (SNP rs3918400) 通过改变微RNA调节来影响儿童喘风险. 这种单核酸多态性影响miR-3928-5p如何控制ADAM33,影响喘严重程度和呼吸道功能.

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