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不受监管的大麻素产品的微小大麻素特征

Erin Johnson¹, Michael Kilgore², Paul Nuzzo³

¹LGC Assure, Lexington, Kentucky, USA.

Cannabis and cannabinoid research

|October 31, 2024

概括

非处方药的CBD产品经常含有各种微小的大麻素,如CBDV和CBG. 然而,它们的度通常不列在标签上,使消费者不了解产品的全部成分.

科学领域:

大麻素科学大麻素科学
植物化学植物化学
分析化学分析化学

背景情况:

关于大麻素的研究主要集中在delta-9-tetrahydrocannabinol (Δ9-THC) 和cannabidiol (CBD) 上.
越来越多的人对轻微大麻素的治疗潜力及其与CBD的相互作用越来越感兴趣.
关于商业产品中轻微大麻素的作用和存在的信息有限.

研究的目的:

量化了15种不同的小大麻素在非处方药 (OTC) CBD产品中的度.
为了比较未受监管的大麻衍生CBD油与受监管的制药对照 (Epidiolex®) 的大麻素特征.

主要方法:

从各种来源收集了80种不同的OTC大麻衍生CBD油品牌的样本.
样品经过溶剂提取和分析,使用液态染色学并联质谱法进行分析.
量化目标是15种特定的轻微大麻素,包括CBDV,CBG,CBC,CBN,CBL和CBDA.

主要成果:

在OTCCBD产品中经常检测到较小的大麻素,其中CBDV (100%),CBG (77%),CBC (72%),CBN (67%) 和CBL (67%) 是最常见的.
在51%的样本中发现了大麻酸 (CBDA),而没有检测到delta-8-tetrahydrocannabinol (Δ8-THC).
观察到的轻微大麻素度差异很大,从微量到几毫克/毫升.

结论:

场外CBD产品通常含有一系列轻微的大麻素,但它们的类型和数量在品牌之间存在很大差异.
产品标签经常省略有关微量大麻素含量的信息,阻碍了消费者意识.
需要进一步的研究来了解这些同时发生的大麻素的临床意义和协同效应.

关键词:

在这里,我们可以看到CBD CBD CBD CBD.分析化学分析化学在Cannabidiol中使用.较小的大麻素是较小的大麻素.监管监管监管监管监管监管

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