[唾液离子度的相关性,Streptococcus和Bifidobacterium在有的儿童中]
Hui-Hui Bian1, Yu Liu, Qing Huang
1Department of Stomatology, Second People's Hospital of Hefei. Hefei 230011, China.
Shanghai kou qiang yi xue = Shanghai journal of stomatology
|October 31, 2024
概括
增加的唾液离子度和链球菌和Bifidobacterium的水平与儿童更严重的牙损伤有关. 这些因素显示出在儿科牙科健康中评估疾病严重程度的潜力.
科学领域:
- 儿科牙科 儿科牙科
- 口腔微生物学 口腔微生物学
- 生物化学 生物化学
背景情况:
- 牙损是儿童常见的一种疾病.
- 了解与病严重程度相关的生化和微生物因素对于有效管理至关重要.
- 唾液成分和特定的细菌形状与脏病的发展有关.
研究的目的:
- 调查唾液离子度 (特别是离子) 与牙损伤儿童中Streptococcus和Bifidobacterium物种的丰富程度之间的相关性.
- 为了确定这些唾液标记物与牙腐烂的严重程度之间的关系,根据腐烂,缺失和填充牙指数 (DMFT) 表示.
- 评估唾液离子度和细菌水平的诊断价值,以评估儿童脏严重程度.
主要方法:
- 一项涉及80名患有牙损伤的儿童 (根据DMFT指数分为轻度和重度组) 和80名健康对照的研究.
- 使用计方法测量唾液离子度.
- 使用实时定量PCR对Streptococcus mutans,Streptococcus sobrinus和Bifidobacterium进行量化.
- 统计分析包括皮尔森相关性和接收器运行特征 (ROC) 曲线分析以评估诊断价值.
主要成果:
- 与对照人群相比,患有牙损伤的儿童的唾液离子,Streptococcus mutans,Streptococcus sobrinus和Bifidobacterium水平显著更高.
- 严重虫组显示出这些标志物的度明显高于轻度虫组.
- 在DMFT指数和唾液离子度,Streptococcus和Bifidobacterium水平之间观察到显著的正相关性.
- ROC分析表明,这些标志物在评估病严重程度时具有不同程度的诊断价值,唾液离子度显示最高的AUC (0.760).
结论:
- 升高的唾液离子度和增加的特定链球菌和Bifidobacterium物种水平与儿童牙损伤的存在和严重程度有关.
- 这些唾液标记物显示出与疾病严重程度的正相关性.
- 唾液离子度,Streptococcus mutans,Streptococcus sobrinus和Bifidobacterium有可能作为评估儿科患者牙损伤严重程度的指标.
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