相关实验视频

Updated: Jun 9, 2025

Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells

Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells

Published on: October 10, 2017

黄素对人类健康的影响:对103项随机对照试验的综合系统审查和元分析

Ali Jafari^1,2, Maryam Abbastabar³, Alireza Alaghi^2,4

¹Student Research Committee, Department of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Phytotherapy research : PTR

|October 31, 2024

概括

黄素补充剂对禁食血糖,脂质概况和炎症标志物产生显著影响. 需要进一步的高质量试验来确认这些好处对各种健康结果.

科学领域:

药理学和治疗学药理学和治疗学
营养科学营养科学
基于证据的医学基于证据的医学

背景情况:

黄素来自Curcuma longa L.,因其潜在的健康益处而得到认可.
许多随机临床试验 (RCT) 研究了黄素对各种健康结果的影响.
对现有证据进行全面的综合分析对于了解黄素的治疗潜力至关重要.

研究的目的:

进行一项元分析,评估黄素补充剂对广泛健康结果的影响.
综合来自RCT的证据,将黄素与安慰剂进行比较.
用GRADE标准评估每个结果的证据确定性.

主要方法:

在PubMed,EMBASE,Scopus和Web of Science数据库中进行系统搜索,截至2023年9月.
包括将Curcuma longa L. (黄素) 与安慰剂进行比较的RCT.
使用随机效应模型对效应大小的元分析;评估偏差风险和证据确定性.

主要成果:

纳入了103个带有7216名参与者的RCT,检查了42个结果.
在42个结局中的23个结局 (55%) 观察到统计学意义上的影响.
高确定性证据支持黄素对禁食血糖 (FBS),C反应蛋白 (CRP),高密度脂蛋白 (HDL) 和体重的影响.

结论:

黄素补充剂对FBS,血糖指数,脂质概况和炎症/氧化标志物产生积极影响.
证据质量各不相同,对特定的代谢和炎症标志物具有很高的确定性.
建议进一步进行精心设计,大规模,长期的RCT,以加强证据基础.

关键词:

库尔库明是一种黄素.与健康相关的结果.人类健康人类健康人类健康黄是一种黄黄的黄.

更多相关视频

Author Spotlight: Eco-friendly Photoluminescent Textile Authentication with Curcumin

Author Spotlight: Eco-friendly Photoluminescent Textile Authentication with Curcumin

Published on: December 22, 2023

Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea

Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea

Published on: December 23, 2022

相关概念视频

Cancer Prevention

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

NF-κB-dependent Signaling Pathway

NF-κB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The...

Hazard Ratio

Hazard Ratio

The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
For example, in a clinical trial...