探索急性性的表型特征:来自第三级儿科急诊室的见解
Sareh Hosseinpour1,2, Roxana Pazouki3, Mahmoud Reza Ashrafi1
1Pediatric Neurologist, Myelin Disorders Clinic, Pediatric Neurology Division, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Iranian journal of child neurology
|October 31, 2024
概括
吉兰-巴雷综合征 (GBS) 是导致急性性 (AFP) 的首要原因,儿童出现在儿科急诊室. 其他诊断包括病毒性肌肉炎,横向髓炎综合征 (TMS) 和疫苗相关性麻性脊髓炎 (VAPP).
科学领域:
- 儿科神经学 儿科神经学
- 传染性疾病 传染性疾病
- 临床研究 临床研究
背景情况:
- 儿童急性软性 (AFP) 有多种潜在的病因.
- 在儿科紧急情况中了解AFP引起的范围对于及时诊断和管理至关重要.
研究的目的:
- 为了调查AFP在儿童中的诊断模式,转诊给儿科急诊室.
- 确定AFP最常见的原因以及任何相关的临床或诊断发现.
主要方法:
- 在2011年至2016年期间,对118名患有AFP的儿童进行了回顾性分析.
- 包括临床数据,便和脑脊液分析,电生理学和成像研究.
主要成果:
- 吉兰-巴雷综合征 (GBS) 是最常见的诊断 (80例).
- 其他重要原因包括急性病毒性肌肉炎 (20例),横向肌肉炎综合征 (TMS) (6例) 和疫苗相关性麻性脊髓炎 (VAPP) (6例).
- 所有VAPP病例都与原发性免疫缺陷有关,所有患者的脊髓灰质炎病毒检测结果均为阴性.
结论:
- 基于医院的研究揭示了与基于社区的研究相比,AFP引起的模式不同.
- 病毒性脑膜炎很少会出现类似AFP的症状.
- 建议对VAPP病例进行初级免疫缺陷评估,并实施了儿科AFP管理协议.
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