使用基本繁殖比来量化传播,并确定动物出血性疾病病毒的数据缺口
1The Pirbright Institute, Ash Road, Pirbright, Surrey GU24 0NF, UK.
Royal Society open science
|October 31, 2024
概括
动物性出血性疾病病毒 (EHDV) 在欧洲的传播取决于温度. 这项研究量化了EHDV的数量.
科学领域:
- 兽医病毒学 兽医病毒学
- 流行病学 流行病学
- 关节动物传播的病毒
背景情况:
- 动物性出血性疾病病毒 (EHDV) 是一种树状病毒,由Culicoides咬传播.
- 最近,欧洲出现了EHDV,对牲畜和野生动物构成威胁.
研究的目的:
- 使用基本的复制比率 (R0) 来量化EHDV传输.
- 确定牛和鹿中EHDV传播的温度依赖性.
- 确定影响EHDV传输的关键参数,并突出研究数据缺口.
主要方法:
- 估计R0参数使用贝叶斯方法与已发表的文献数据.
- 在R0计算中包含不确定性.
- 使用Sobol方法进行灵敏度分析,以确定有影响力的参数.
主要成果:
- 根据EHDV菌株,最大R0从0.7-2.5在牛中和1.3-4.3在鹿中变化.
- 最大R0的最佳温度为22-25°C.
- 在16-20°C的温度下,R0超过1.
- 影响R0的关键参数包括病毒复制的值温度,宿主-载体传播概率和载体-宿主比率.
结论:
- 电动高频汽车的传输取决于温度,具有特定的最佳和最低传输温度.
- 关于欧洲鹿中的EHDV和野生动物-牲畜界面的传播动态,存在重大数据缺口.
- 未来的研究应该专注于这些已识别的数据缺口,以有效管理EHDV.
更多相关视频
11:12Protocols for Investigating the Host-tissue Distribution, Transmission-mode, and Effect on the Host Fitness of a Densovirus in the Cotton Bollworm
Published on: April 12, 2017
8.4K
08:02Experimental Viral Infection in Adult Mosquitoes by Oral Feeding and Microinjection
Published on: July 28, 2022
2.2K
相关概念视频
Infection
11.6K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
11.6K
Infectious Diseases and Their Occurrence
94
Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable...
94
Investigation of Disease Outbreaks
74
Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
74
