患有先前严重精神疾病的人群中妄想风险和死亡率:使用英格兰链接数据集进行的回顾性队列研究
Yehudit Bauernfreund1,2, Naomi Launders1, Graziella Favarato1
1Division of Psychiatry, University College London, London W1T 7BN, UK.
Psychological medicine
|October 31, 2024
概括
患有严重精神疾病的人 (SMI) 患上妄想诊断的风险更高. 这项研究发现SMI和妄之间存在关联,这表明医院环境中的脆弱性增加.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 妄想是一种严重的神经精神综合征,与高死亡率有关.
- 识别妄风险因素对于预防和查至关重要.
- 严重精神疾病 (SMI) 和妄想风险之间的关系是未知的.
研究的目的:
- 为了确定先前存在的SMI诊断是否会增加妄想症的风险.
- 为了调查SMI是否与妄诊断后的死亡率更高有关.
主要方法:
- 追溯的队列和嵌套病例控制研究 (2000-2017).
- 连接初级和二级医疗保健数据库.
- 在SMI患者中比较妄发病率和30天死亡率与匹配的非SMI比较者.
主要成果:
- 确定了20,566名SMI患者和71,374名比较者.
- 对于所有SMI亚型来说, Delirium诊断的风险更高,特别是在65岁以下的人中.
- 在SMI和非SMI组之间,在狂妄病住院后30天死亡率没有显著差异.
结论:
- 在SMI和妄想诊断之间存在关联.
- 患有SMI的个人在医院环境中可能更容易患上妄想症.
- 需要进一步的前性研究来验证由于电子健康记录的局限性而导致的发现.
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