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Updated: Jun 9, 2025

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates
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使生物结合化学物质成为可能

Mengmeng Zheng1, Lingchao Kong1, Jianmin Gao1

  • 1Department of Chemistry, Merkert Chemistry Center, Boston College, 2609 Beacon Street, Chestnut Hill, MA 02467, USA. jianmin.gao@bc.edu.

Chemical Society reviews
|October 31, 2024
PubMed
概括

支持的生物结合反应提供了独特的生物相容性和可调节的可逆性. 这篇评论分析了.

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Labeling DNA Probes03:31

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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