Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Labeling DNA Probes03:31

Labeling DNA Probes

8.1K
DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
8.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Association of the Fibrosis-4 index with thyroid nodule prevalence in women: a cross-sectional study.

BMC endocrine disorders·2026
Same author

Stirring-directed pathway selection between 1D nanofibers and multilayer sheet-like assemblies in supramolecular polymerization.

Chemical communications (Cambridge, England)·2026
Same author

Correlation and regression analysis of the <i>KRT27</i> and <i>ELOVL4</i> genes in cashmere fineness and other production performances in Liaoning cashmere goats.

Archives animal breeding·2026
Same author

Relationship between β-arrestin1-GAPDH interaction and the DADLE-mediated protection of brain microvascular endothelial cells from hypoxia-ischemic/reperfusion injury.

European journal of pharmacology·2026
Same author

Sex-specific effects of <i>guanosine monophosphate synthase</i> and <i>steroid receptor coactivator</i> gene polymorphisms on cashmere fineness and production traits in Liaoning Cashmere goats.

Veterinary world·2026
Same author

Extensive Isolated Intracranial Recurrence of Primary Mediastinal B-Cell Lymphoma on FDG PET Imaging.

Clinical nuclear medicine·2026
Same journal

Direct impure water electrolysis at industrial scale.

Chemical Society reviews·2026
Same journal

Catalytic valorization of polyolefins: from catalysts and processes to reactors.

Chemical Society reviews·2026
Same journal

Designing stable π-radicals.

Chemical Society reviews·2026
Same journal

Antibacterial drug discovery: challenges and preclinical promises from synthetic small molecules.

Chemical Society reviews·2026
Same journal

Selective carbon-carbon bond cleavage involving alkene moieties.

Chemical Society reviews·2026
Same journal

Circularly polarized luminescence: an easy path from molecules to supramolecular systems and beyond.

Chemical Society reviews·2026
查看所有相关文章

相关实验视频

Updated: Jun 9, 2025

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates
08:47

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates

Published on: March 6, 2019

9.4K

使生物结合化学物质成为可能.

Mengmeng Zheng1, Lingchao Kong1, Jianmin Gao1

  • 1Department of Chemistry, Merkert Chemistry Center, Boston College, 2609 Beacon Street, Chestnut Hill, MA 02467, USA. jianmin.gao@bc.edu.

Chemical Society reviews
|October 31, 2024
PubMed
概括
此摘要是机器生成的。

支持的生物结合反应提供了独特的生物相容性和可调节的可逆性. 这篇评论分析了.

更多相关视频

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
12:31

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry

Published on: August 19, 2012

24.3K
The Use of a &#946;-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions
08:06

The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions

Published on: February 1, 2018

9.0K

相关实验视频

Last Updated: Jun 9, 2025

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates
08:47

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates

Published on: March 6, 2019

9.4K
Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
12:31

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry

Published on: August 19, 2012

24.3K
The Use of a &#946;-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions
08:06

The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions

Published on: February 1, 2018

9.0K

科学领域:

  • 化学 化学 化学
  • 生物结合化学 生物结合化学
  • 材料科学 材料科学 材料科学

背景情况:

  • 生物结合反应对于分子标记和材料构造至关重要.
  • 的独特特性,包括生物相容性,导致了新的生物结合策略.
  • 现有的方法往往缺乏可调整的可逆性或广泛的生物对等应用性.

研究的目的:

  • 总结和比较分析介导生物结合的近期进展.
  • 讨论启用反应的热力学和动力学概况.
  • 为在各种生物应用中应用这些反应提供准则.

主要方法:

  • 审查和分析最近开发的介导生物结合反应.
  • 热力学和运动性质的比较评估.
  • 在有机试剂中探索结构-反应性关系.

主要成果:

  • 支持的生物结合体显示出显著的生物相容性和可调节的可逆性.
  • 已经实现了快速可逆和稳定的共价生物结合.
  • 这些反应扩大了生物对角化学和可逆共价抑制的范围.

结论:

  • 介导化学为开发先进的生物结合策略提供了一个多功能平台.
  • 了解热力学和动力学概况是优化反应设计的关键.
  • 这些发现为化学生物学和材料科学的未来应用提供了宝贵的见解.