胺基质子转移MRI可以反映有效的再注射,并预测缺血性中风患者的功能结果
Chi Zhang1, Xingwang Yong2, Yuezhou Cao3
1Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
概括
胺基质子转移 (APT) 成像在评估中风后组织恢复方面显示出希望. 在急性缺血性中风患者中,APT成像可以预测大血管封闭的90天功能结果.
科学领域:
- 神经成像是一种神经成像.
- 脑卒中医学 脑卒中医学
- 生物化学 生物化学
背景情况:
- 输液成像对于评估急性缺血性中风 (AIS) 组织恢复至关重要,但并不反映组织代谢.
- 重灌后的组织状况的特征对于预测患者的结果至关重要.
研究的目的:
- 调查胺质子转移 (APT) 成像对AIS大血管封闭 (LVO) 患者90天功能结果的预后价值.
- 为了确定APT成像是否可以在反疗法后描述组织状况.
主要方法:
- 包括63名患有AIS和LVO的患者.
- 量化了APT和NOE (核Overhauser增强) 的信号.
- 在APT和扩散权重成像 (DWI) 上的缺血病变被根据不匹配模式 (APT < DWI;APT ≥ DWI) 分类.
主要成果:
- 成功的再输血与更高的APT信号和更高的APT
- APT信号和APT
- APT ≥ DWI不匹配表明即使在成功的再输液后,结果也很差.
- APT信号和APT
结论:
- 在AIS患者中,APT成像可能会揭示AIS患者的再输血后组织恢复.
- 在LVO的AIS中,APT成像显示出作为90天功能结果的预后工具的潜力.
关键词:
缺血性中风是因为缺血性中风.这是一种酸性症.氨基酸胺转移质子转移perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion 这是一个非常重要的方法,它可以让一个人的身体变得更加舒适,可以让一个人的身体变得更加舒适,可以让一个人的身体变得更加舒适预后 预后 预后
相关概念视频
01:24Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
01:15Ischemic Stroke ll: Pathophysiology
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...