天然蜂蜜蛋白质可以预防大鼠的饮食引起的肥胖和代谢障碍
Atia Gohar1, Richard L Atkinson2,3, Darakhshan J Haleem2
1H.E.J. Research Institute of Chemistry, ICCBS, University of Karachi, Karachi, Pakistan.
Journal of medicinal food
|October 31, 2024
概括
蜂蜜蛋白 (HP) 通过提高体重增加效率而没有改变能量摄入,有效地减少了大鼠的体重增加. 这表明HP可能会增加新陈代谢率,这需要进一步对人类进行研究.
科学领域:
- 生物化学 生物化学
- 营养科学 营养科学
- 代谢研究研究 代谢研究
背景情况:
- 在之前的研究中,食用整个蜂蜜已经证明减轻体重增加和抗炎作用.
- 蜂蜜中对这些代谢益处负责的特定成分在很大程度上仍未确定.
研究的目的:
- 研究蜂蜜蛋白 (HP) 在调节体重增加和肥胖指标中的作用.
- 为了确定HP是否可以通过影响能量摄入,体重和基因表达来缓解肥胖.
主要方法:
- 蛋白质被用盐分法从白木蜂蜜中分离出来.
- 维斯塔鼠被养正常或高脂肪饮食,然后用HP或盐水治疗4周.
- 测量包括能量摄入量,体重增加,血清葡萄糖,脂质和脂肪组织基因表达 (FABP,LIPC,APOA1).
主要成果:
- 与对照组相比,HP治疗显著减少了正常饮食和高脂肪饮食组的体重增加.
- 体重增加效率 (每克体重增加的能量摄入量) 被HP显著降低.
- 在正常饮食小鼠中,HP降低了血清葡萄糖,在两个饮食组中降低了甘油三.
结论:
- 蜂蜜蛋白 (HP) 显著提高体重增加效率,而不会影响大鼠的总体能量摄入量.
- 惠普治疗显示出减轻肥胖指标的潜力,需要在人类实验中进行进一步的研究.
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