在脊椎裂骨髓瘤中,体结构和听觉半球间转移在脊椎裂骨髓中
Kailyn A Bradley1, Jenifer J Juranek2, H Julia Hannay1
1Department of Psychology, University of Houston.
Neuropsychology
|October 31, 2024
概括
脊柱裂骨髓瘤 (SBM) 的后半球体质体发育不良会破坏听觉半球间传输. 这种转移的保存取决于体的后部连接和潜在的前部结局通路.
科学领域:
- 神经科学是一个神经科学.
- 发育神经科学的发展神经科学.
- 神经成像是一种神经成像.
背景情况:
- 体后部发育不良经常发生在脊柱裂骨髓瘤 (SBM) 中.
- 这种发育不良源于与水脑发育相关的低成形和先天性部分低成形.
- 体对半球间的通信至关重要.
研究的目的:
- 研究半球间道的宏观和微观结构完整性之间的关系.
- 为了检查SBM患者的听觉半球间传输,使用辅音-母音二语听力.
主要方法:
- 收集了T1加权和扩散张力成像数据,来自46名SBM患者和15名典型的发展对照.
- 利用概率学曲谱学来隔离连接听觉区域的半球间白质.
- 评估半球间转移使用辅音-母音二语听力任务.
主要成果:
- 这两组都表现出典型的右耳优势,但SBM患者较少表现出这种优势.
- 在SBM小组中,右耳优势的缺失在脊髓代或严重的后部低成形时突出.
- 性别,前部指导管的大小和分流通路的数量预测了右耳的优势.
结论:
- 半球间转移在SBM和后半身质体低发症患者中受损.
- 保存的半球间转移与完整的后半身结质连接有关.
- 通过前 commissure 的补偿通路可能在维持转移方面发挥作用.
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