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Luca Pierantoni¹, Fabrizio Vecchio², Francesca Miraglia²

¹Brain Connectivity Laboratory, Dept. Neuroscience & Neurorehabilitation, IRCCS San Raffaele, Rome, Italy; The Biorobotics Institute and Department of Excellence in Robotics and AI, Scuola Superiore Sant'Anna, Pontedera, Italy.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

|October 31, 2024

概括

通过皮肤脊髓直流刺激 (tsDCS) 通过增加脊髓刺激性来增强手部肌肉反应. 这种神经调节技术在皮层脊髓损伤的个体中显示出改善运动功能的潜力.

科学领域:

神经科学是一个神经科学.
神经生理学神经生理学
康复科学康复科学康复科学

背景情况:

脊髓刺激性对于运动控制至关重要.
非侵入性脑刺激技术提供潜在的治疗益处.
了解神经调节对脊髓的影响是临床应用的关键.

研究的目的:

研究通过皮肤进行脊髓直流刺激 (tsDCS) 对脊髓刺激性的影响.
为了确定调节脊髓功能的最佳tsDCS参数.
探索底层的神经生理机制 tsDCS诱导的变化.

主要方法:

在18名年轻志愿者身上进行了一项模拟控制的随机实验.
脊髓运动神经元刺激性被评估使用跨磁刺激 (TMS),F波和体感唤起潜能.
测试了四种不同的 tsDCS 安装,其中最有效的安装应用了 18 分钟.

主要成果:

最佳的tsDCS安装包括将阳极放置在第七个椎脊柱上,并将阴极放置在光上.
在tsDCS期间观察到手肌对TMS的运动反应显著增强 (p<0.00001).
这种促进效应在6分钟后达到平原,并在刺激后迅速下降.

结论:

tsDCS可以促进椎水平上的运动神经元的神经调节.
增强的脊髓刺激性表明,对于皮质脊髓通路受损的个体有潜在的应用.
这项研究强调了tSDCS作为运动功能康复的有希望的工具.

关键词:

发动机唤起了潜在的潜力.神经康复疗法神经康复疗法身体感官唤起潜在的潜力.脊髓是指脊髓中的一些部分.通过骨磁刺激来进行磁性刺激.通过皮肤进行脊柱直流刺激.

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