多不和脂肪酸在怀孕和哺乳期间的影响:综合性综述
Yasna Muñoz1, Lorena Mercado2, Camila Farias3
1Department of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile; Escuela de Nutrición y Dietética, Facultad de Farmacia, Universidad de Valparaíso, Chile.
Prostaglandins, leukotrienes, and essential fatty acids
|October 31, 2024
概括
足够的多可萨赫萨酸 (DHA) 摄入量和均衡的n-6/n-3多不和脂肪酸 (PUFA) 比例对于婴儿大脑发育至关重要,特别是在肥胖的孕妇中. 本综述汇集了关于DHA和ARA在怀孕和哺乳期间的证据.
科学领域:
- 母婴营养 母婴营养
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 达可沙赫萨酸 (DHA) 和阿拉基酸 (ARA) 是重要的多不和脂肪酸 (PUFA),在怀孕和哺乳期间对胎儿和婴儿发育至关重要.
- 妊娠期肥胖会改变母亲的脂质样本,增加n-6PUFA的消耗,需要修订PUFA建议.
研究的目的:
- 提供关于DHA和ARA在妊娠和哺乳期间的作用的科学证据的最新审查.
- 突出这些脂肪酸对新生儿发育的重要性.
主要方法:
- 在包括PubMed,Scopus,Web of Science,Scielo,ISI和Ovid MedLine在内的主要科学数据库中进行全面的文献搜索.
- 专注于研究DHA和ARA对婴儿神经发育的重要性.
主要成果:
- 足够的母体摄入n-3PUFA,特别是DHA,支持婴儿正常大脑发育.
- 虽然母体的DHA补充会提高母体的DHA水平,但它对婴儿神经发育的直接影响需要进一步澄清.
- 孕产妇的肥胖会破坏n-3/n-6PUFA平衡,而足够的DHA摄入会有益于儿童的认知功能,并可能影响其炎症概况.
结论:
- 理想的母体DHA摄入量和适当的n-6/n-3PUFA比对婴儿在妊娠和哺乳期间的生长和大脑发育至关重要.
- 对于肥胖的孕妇,建议特别注意DHA和n-6/n-3PUFA比率,以支持胎儿的发育.
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