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Updated: Jun 9, 2025

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3D基因组拓学区分了脑髓母细胞瘤的分子子组

John J Y Lee1, Michael J Johnston2, Hamza Farooq1

  • 1The Arthur and Sonia Labatt Brain Tumor Research Center, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G 1L7, Canada.

American journal of human genetics
|October 31, 2024
PubMed
概括

拓关联域绝缘分数有效区分脑髓母细胞瘤亚型,独立于基因表达. 这种3D基因组架构分析为脑髓母细胞瘤分类提供了新的见解.

关键词:
三维基因组是3D的中枢神经系统的瘤.这就是Hi-C.癌症 癌症 癌症 癌症 癌症脑髓母细胞瘤是什么意思转录组 (transcriptome) 是一个转录组.

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